What to Know in 2019

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It dates back to the 6th century, but bubonic plague is still active in the U.S. Three new cases have been reported in the last six months in cats, but no humans, in Wyoming.

Source: WebMD HealthCategory: Consumer Health News Source Type: news

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(Natural News) The City of Angels is on the verge of succumbing to a deadly disease epidemic, thanks to an out-of-control homeless problem that’s bringing back horrific contagions like bubonic plague that rarely make an appearance in the First World. According to Dr. Drew Pinsky, a celebrity radio doctor who was blacklisted from the mainstream…

Source: NaturalNews.comCategory: Consumer Health News Source Type: news

This article evaluates the textual evidence for bubonic plague in classical antiquity from medical sources and discusses methodologies for “retrospective diagnosis” in light of new developments in microbiology. A close study of Greek medical texts suggests that bubonic plague was unfamiliar to medical writers until sometime before the second century AD, when sources cited by Rufus of Ephesus report a disease that resembles bubonic plague. Rufus of Ephesus describes this disease around AD 100, and Aretaeus (fl. ca. AD 50 or 150) appears to describe the same disease as well. Intriguingly, the disease then disappear…

Source: Medical HistoryCategory: History of Medicine Authors: Tags: Bull Hist Med Source Type: research

Reflexively, I often feel my breath catch, and my eyeballs roll ever-so-slightly when a patient leads with, “I saw on the internet… ” The precious minutes available to connect, inspect, and direct the management of their Google search are suddenly squandered by backtracking to reassure the bug bite will not turn into the bubonic plague! […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.

Source: Kevin, M.D. – Medical WeblogCategory: General Medicine Authors: Tags: Physician Primary Care Source Type: blogs

(Natural News) Another new case of measles has been identified, this time in Los Angeles County where typhoid fever, tuberculosis, and even bubonic plague are making a comeback thanks to rampant illegal immigration and homelessness. But rather than take a step back and evaluate the facts, authorities are once again freaking out about some people…

Source: NaturalNews.comCategory: Consumer Health News Source Type: news

Publication date: Available online 25 June 2019Source: Microbes and InfectionAuthor(s): Christian Demeure, Olivier Dussurget, Guillem Mas Fiol, Anne-Sophie Le Guern, Cyril Savin, Javier Pizarro-CerdáAbstractPlague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from rodent reservoirs, Y. pestis emerged less than 6000 years ago from an enteric bacterial ancestor through events of gene gain and genome reduction. It is a highly remarkable model for the understanding of pathogenic bacteria evolution, and a major concern for public health as highlighted by recent human outbreaks. A complex set o…

We describe a cell culture model for the infection of human neutrophils with Y. pestis. Neutrophils are isolated from human peripheral blood at high purity and subsequently infected with Y. pestis. We specifically focus on the application of this in vitro infection assay to the analysis of neutrophil degranulation responses.
PMID: 31177440 [PubMed – in process]

Source: Mol Biol CellCategory: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research

A quick overview of three medical stories that are worth a mention.Medscape

Source: Medscape Today HeadlinesCategory: Consumer Health News Tags: Internal Medicine Article Source Type: news

Bubonic plague did not entirely disappear after the “Black Death” outbreaks of the Middle Ages

A local folk remedy thought to provide good health had the opposite effect for one Mongolian couple: After eating the raw kidney of a marmot, the pair died of bubonic plague, AFP news agency reported on Monday. Health authorities responded by declaring a quarantine that included locals and foreign tourists who had come into contact with the couple.

Source: CNN.com – HealthCategory: Consumer Health News Source Type: news



Qingwen Zhang1†, Youquan Xin1†, Haihong Zhao1, Rongjiao Liu2, Xiaoqing Xu1, Yanfeng Yan2, Zhipeng Kong1, Tong Wang2, Zhizhen Qi1, Qi Zhang1, Yang You2, Yajun Song2, Yujun Cui2, Ruifu Yang2*, Xuefei Zhang1* and Zongmin Du2*

1Qinghai Institute for Endemic Disease Prevention and Control, Xining, China
2State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

Yersinia pestis is the etiological agent of the notorious plague that has claimed millions of deaths in history. Of the four known Y. pestis biovars (Antiqua, Medievalis, Orientalis, and …



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