Why “Desperate Housewives” star is talking about anal cancer

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“Mostly I want to talk about it because I know there are people who are ashamed”

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AbstractIn the U.S. there is an epidemic of sexually transmitted diseases (STIs). One of the most prevalent STIs is the Human Papillomavirus (HPV). Certain high risk strains of HPV are believed to cause virtually all cervical cancers, over 90% of anal cancers, 70% of oropharyngeal cancers, and the majority of anal  genital warts. HPV is preventable through vaccination and is available for both men and women. Several educational interventions have been employed, yet baseline awareness and knowledge related to HPV and 9vHPV remains relatively low among young men. What is not known is the most effective method for provid…

This article examines the various types of perianal cancers and their precursor lesions and will explore treatment options as well as outcomes and prognosis. […] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Publication date: Available online 19 August 2019Source: The American Journal of SurgeryAuthor(s): Katherine Bingmer, Asya Ofshteyn, David Dietz, Sharon L. Stein, Emily SteinhagenAbstractBackgroundImmunosuppressed patients have an increased risk of developing anal cancer, but little data exists regarding outcomes of this population.MethodsA retrospective review of anal cancer patients at a single academic institution from 2006-2017 was performed.Results19 (14%) of 136 anal cancer patients were immunosuppressed. Immunosuppressed patients were more likely to be hypoalbuminemic (21% vs. 6%, p=0.025), less likely to complete c…

ConclusionsOver half of anal cancer patients were initially misdiagnosed, and 25% were symptomatic for more than 6  months prior to diagnosis. Those patients diagnosed earlier tended to be more likely to receive complete chemoradiation therapy. We were unable to show a statistical difference in outcomes between groups. Further investigation into provider education and awareness of anal cancer is warranted to im prove the care of these patients.

To investigate the prognostic significance of positron emission tomography (PET) parameters from F-18 fluorodeoxyglucose (FDG) PET scans performed pre- and post- chemo-radiotherapy (CRT) for squamous cell carc…

Source: Radiation OncologyCategory: Cancer & Oncology Authors: Tags: Research Source Type: research

AbstractStandardized terminology is critical to providing consistent reports to referring clinicians. This lexicon aims to provide a reference for terminology frequently used in rectal cancer and reflects the consensus of the Society of Abdominal Radiology Disease Focused Panel in Rectal cancer. This lexicon divided the terms into the following categories: primary tumor staging, nodal staging, treatment response, anal canal anatomy, general anatomy, and treatments.

Doublet chemotherapies are the mainstay in the management of metastatic anal cancer. Immunotherapy has been incorporated into guidelines in a refractory setting. Treatment options remain limited with tumor progression beyond immunotherapy. Modified  docetaxel, cisplatin, and fluorouracil (mDCF) chemotherapy, after progression postimmunotherapy, has shown a near‐complete response in our patient with metastatic anal cancer. This likely is secondary to the sequence of immunotherapy followed by chemotherapy that is yielding greater than histo rical responses. AbstractDoublet chemotherapies are the mainstay in …

Source: Clinical Case ReportsCategory: General Medicine Authors: Tags: CASE REPORT Source Type: research

CONCLUSIONS: Malignant tumorswere still the main cause of death in one’s life time, giving rise to LDP. LDP caused by malignant tumours has twodivisions. First, traditional upper digestive system cancers related to long-term chronic infection, such as esophagealcancer, gastric cancer, and liver cancer, which has shown a significant downward trend. Second, lung and colorectalcancers related to the environmental factors and lifestyle, which are on the rise.
PMID: 31350960 [PubMed – in process]

ConclusionsInfrared coagulation is a safe and effective method for ablation of high-grade anal dysplasia that could help prevent anal cancer. Continued surveillance is recommended due to the risk of recurrence.

Authors call for new screening strategies for anal cancer prevention in women living with HIV

Source: The Doctors Lounge – OncologyCategory: Cancer & Oncology Tags: Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Oncology, Pathology, Surgery, Journal, Source Type: news



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