Neuroterrorism preparedness for the neurohospitalist

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In this review article, we highlight several potential biologic and chemical agents of “neuroterrorism” of which neurohospitalists should be aware: anthrax, botulism toxin, brucella, plague, smallpox, organophosphates and nerve agents, cyanide, and carfent…

Source: SafetyLitCategory: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

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In conclusion, our study shows that the T-B combined epitopes and CTL epitopes of OMP2b and BCSP31 have immunogenicity and immunoreactivity. Our results may lay a theoretical foundation for the development of vaccines against Brucella.

Source: Molecular ImmunologyCategory: Allergy & Immunology Source Type: research

WEDNESDAY, Sept. 25, 2019 — Jynneos Smallpox and Monkeypox Vaccine, Live, Non-Replicating, was approved by the U.S. Food and Drug Administration for prevention of smallpox and monkeypox disease in adults 18 years or older who are considered at high…

Here’s what is significant about the new Jynneos Smallpox and Monkeypox Vaccine.

Source: Forbes.com Healthcare NewsCategory: Pharmaceuticals Authors: Source Type: news

The approval is in part intended to protect against the potentially devastating consequences of intentional release of the smallpox virus, and the vaccine will be included in the Strategic National Stockpile.FDA Approvals

Source: Medscape Allergy HeadlinesCategory: Allergy & Immunology Tags: Infectious Diseases News Alert Source Type: news

COPENHAGEN, Denmark, September 24, 2019– Bavarian Nordic A/S (OMX: BAVA, OTC: BVNRY) today announced that the U.S. Food and Drug Administration (FDA) has approved Jynneos™ (Smallpox and Monkeypox Vaccine, Live, Non-replicating)…

Dihydroartemisinin inhibits multiplication of Brucella suis vaccine strain 2 in murine microglia BV2 cells via stimulation of caspase‑dependent apoptosis.
Mol Med Rep. 2019 Sep 11;:
Authors: Yang J, Li H, Wang Z, Yu L, Liu Q, Niu X, Xu T, Wang Z
Abstract
Brucellosis, caused by a facultative intracellular parasite Brucella species, is the most common bacterial zoonotic infection worldwide. Brucella can survive and proliferate in several phagocytic and non‑phagocytic cell types. Human brucellosis has similar clinical symptoms with systemic diseases, which may lead to delay of diagnosis and increasing…

Source: U.S. Food and Drug Administration (FDA). Published: 9/24/2019.
This six-page document details the Food and Drug Administration (FDA)’s approval of Jynneos Smallpox and Monkeypox Vaccine, Live, Non-Replicating, for the prevention of smallpox and monkeypox disease in adults 18 years of age and older determined to be at high risk for smallpox or monkeypox infection. This is the only currently FDA-approved vaccine for the prevention of monkeypox disease. This vaccine is also part of the Strategic National Stockpile (SNS).
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In this report, we extracted the essential oil from the aerial parts of the A. tenuifolia (collected from Khoy), at various developmental stages (i.e. vegetative, flowering and fruiting), characterize them and study their antibacterial activities. Of 46, 51 and 38 components found in the vegetative, flowering, and fruiting stages, respectively, 35 were present in all three stages, including oxygenated terpenes such as carvacrol (30.85-34.11), germacrene-C (17.87-16.21), spathulenol (8.96-7.26), β-sesquiphellandrene 4.25-4.11), t-muurolol (3.25-2.27) and α-cadinol (3.29-2.01). We witnessed that the composition of…

Source: Chemistry and BiodiversityCategory: Biochemistry Authors: Tags: Chem Biodivers Source Type: research

As families face back-to-school medical requirements this month, the country feels the impact of a vaccine resistance movement decades in the making.

Source: NYT HealthCategory: Consumer Health News Authors: Tags: your-feed-science Vaccination and Immunization Smallpox Whooping Cough Children and Childhood Human Papillomavirus (HPV) Measles Parenting Autism Medicine and Health Babies and Infants Doctors Rumors and Misinformation Centers fo Source Type: news

Malaria elimination and eventual eradication will require internationally coordinated approaches; sustained engagement from politicians, communities, and funders; efficient organizational structures; innovatio…

Source: Malaria JournalCategory: Infectious Diseases Authors: Tags: Review Source Type: research



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