Authors call for new screening strategies for anal cancer prevention in women living with HIV
We report the incidence and time trends of anal cancer in PLWHIV in Australia.
A data linkage study between the National HIV Registries and the Australian Cancer Database.
Cases of anal squamous cell carcinoma (ASCC) in Australians aged 16 years and above diagnosed with HIV between 1982 and 2012 were identified. Standardized incidence ratios (SIRs) were calculated to compare incidence with that of the general population. Poisson regression models were developed to describe the time trends of ASCC over time and to compare ASCC risk within subgroups of PLWHIV.
Among 28 696 individua…
(Natural News) It used to be that AIDS was widely regarded as the “gay disease.” But now it’s a transgender disease as well, with new data published by the U.S. Centers for Disease Control and Prevention (CDC) showing that an astounding one in seven transgender “women” are infected with HIV. According to a CDC “Dear…
The advent of highly active antiretroviral therapy (HAART) has significantly reduced the incidence of AIDS events, including AIDS-defining malignancies. Nevertheless, several cohort studies conducted in the post-HAART period have reported an increasing risk of non-AIDS-defining cancers (NADC). Overall, the potential mechanisms leading to an increased risk of developing NADCs probably involve multiple known and unknown factors. In addition to ageing, chronic inflammation and ongoing immune system dysregulation, other contributing factors are the co-infection with potentially oncogenic viruses (HBV, HCV, HP…
ConclusionsThe A-HRSI is able to reliably assess participant-reported symptoms and impacts of anal HSIL across a 7 –10 days of timeframe. Future work will involve the establishment of construct and discriminant validity prior to inclusion in the full ANCHOR trial.
This article reviews the current literature on HPV-associated anal cancer in the HIV-infected population, including epidemiology, screening, clinical characteristics, and treatment outcomes.
PMID: 30523625 [PubMed – in process]
CONCLUSION: Incorporation of an early anal cancer detection programme into routine HIV clinical care for MSM living with HIV showed high patient acceptability, uncommon adverse outcomes and specialist referral patterns similar to other cancer screening programmes.
PMID: 30516346 [PubMed – in process]
Is high-resolution anoscopy an effective and tolerable means of screening HIV patients at high risk of anal cancer?HIV Medicine
CONCLUSIONS: HL- and HPV-related neoplasms are the commonest NADC in a cancer referral hospital from a middle-income country with universal access to cART since year 2005. Screening for early anogenital lesions should be emphasized in patients with HIV. It is essential to establish multidisciplinary groups involving Hemato-oncologists, Oncologists, Gynecologists, and HIV Specialists in the treatment of these patients.
PMID: 30368240 [PubMed – in process]
ConclusionsHIV ‐infected Hispanics have an elevated risk for HPV‐related cancers. Similarly to the general population, HIV‐infected Hispanics have higher rates of cervical and penile cancer than NHWs and NHBs. HPV vaccination should be promoted among HIV‐infected individuals to reduce the burden of HPV‐r elated cancers.
(Natural News) The Twitter thought police recently blocked a widely-respected, pro-life news outlet from accessing its account over a four-year-old tweet that contained facts about how homosexual men are prominent carriers of sexually-transmitted diseases (STDs). Dr. Gerard M. Nadal, a molecular biologist and microbiologist who also serves as president and CEO of the Coalition on…