Live from Geneva: Q & A on #Dengue


Source: World Health Organization (WHO). Published: 8/14/2019. This 25-minute video features live responses from an expert to questions about dengue, which is transmitted through Aedes aegypti and Aedes Albopictus mosquitoes, also known as Asian tiger mosquitoes. These are the same mosquitoes that transmit chikungunya, yellow fever, and Zika. Topics include identifying the warning signs and symptoms of severe dengue, and complications caused by dengue. (Video or Multimedia)

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Publication date: Available online 16 August 2019Source: MicronAuthor(s): Lilian Mirian Oliveira de Morais, Eduardo Inocente Jussiani, João Antonio Cyrino Zequi, Paulo José dos Reis, Avacir Casanova AndrelloAbstractAedes aegypti and Aedes albopictus are vectors of several arboviruses responsible for causing dengue, chikungunya, Zika, and yellow fever viruses and microcephaly, resulting in a public health problem in several countries worldwide. Even in this scenario, studies on the morphology of mosquito eggs are still lacking. In this paper, X-ray microtomography was used to study mosquito egg morphology. Sev…

Source: Micron – August 17, 2019Category: Biology Source Type: research

Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with …

Source: PediatricEducation.org – July 29, 2019Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

The present study shows that the most prominent human arboviruses worldwide (dengue viruses 1, 2, 3, and 4, Chikungunya virus, and Zika virus) can infect wild animals and jump from urban to sylvatic maintenance cycles in South America, as did the yellow fever virus in the past. All these viruses are transmitted by the anthropophilic mosquito Aedes aegypti and cause epidemics throughout Brazil. The yellow fever virus is the oldest example of an urban arbovirus that became sylvatic in South America. Currently, the disease is a zoonosis of non-human primates that moves like a wave through forests of the Brazilian countryside,…

Authors: Kim YH, Kim TY, Park JS, Park JS, Lee J, Moon J, Chong CK, Junior IN, Ferry FR, Ahn HJ, Bhatt L, Nam HW Abstract A rapid diagnostic test (RDT) kit was developed to detect non-structural protein 1 (NS1) of yellow fever virus (YFV) using monoclonal antibody. NS1 protein was purified from the cultured YFV and used to immunize mice. Monoclonal antibody to NS1 was selected and conjugated with colloidal gold to produce the YFV NS1 RDT kit. The YFV RDTs were evaluated for sensitivity and specificity using positive and negative samples of monkeys from Brazil and negative human blood samples from Korea. Among monoc…

Failloux Although the role of exogenous small interfering RNA (siRNA) and P-element induced wimpy testis (PIWI)-interacting RNA (piRNA) pathways in mosquito antiviral immunity is increasingly better understood, there is still little knowledge regarding the role of mosquito cellular microRNA (miRNA). Identifying direct interactions between the mosquito miRNAs and the RNA genome of arboviruses and choosing the relevant miRNA candidates to explore resulting antiviral mechanisms are critical. Here, we carried out genomic analyses to identify Aedes aegypti miRNAs that potentially interact with various lineages and genotyp…

Source: Viruses – June 10, 2019Category: Virology Authors: Yen Chen Sreenu Kohl Failloux Tags: Article Source Type: research

This study shows spatiotemporal variability in IR inAe.aegypti populations in southern coastal Ecuador, and provides an initial examination of IR in this region, helping to guide vector control efforts forAe.aegypti.

This study lays critical groundwork for pursuing ZIKV transmission-blocking strategies that exploit the Ae. aegypti exo-siRNA response for arbovirus suppression in natural populations. PMID: 31103782 [PubMed – as supplied by publisher]

Source: Insect Biochemistry and Molecular Biology – May 16, 2019Category: Biochemistry Authors: Magalhaes T, Bergren NA, Bennett SL, Borland EM, Hartman DA, Lymperopoulos K, Sayre R, Borlee BR, Campbell CL, Foy BD, Olson KE, Blair CD, Black W, Kading RC Tags: Insect Biochem Mol Biol Source Type: research

Mosquitoes are considered the most important vectors for the transmission of pathogens to humans.Aedes aegypti is a unique species, not only by its highly anthropophilic and peridomestic habits but also because it can transmit an important variety of pathogenic viruses. Examples are dengue, yellow fever, chikungunya, Zika, and Mayaro viruses. After ingesting viremic blood, a wide range of mechanisms are activated in the mosquito to counteract viral infection. Nevertheless, these arboviruses possess strategies to overcome barriers in the mosquito and eventually reach the salivary glands to continue the transmission cycle. H…

Source: Intervirology – May 13, 2019Category: Virology Source Type: research

Publication date: May 2019Source: Saudi Journal of Biological Sciences, Volume 26, Issue 4Author(s): Aarti Sharma, Sarita Kumar, Pushplata TripathiAbstractAedes aegypti L. is the primary vector associated with transmission of globally concerned diseases; Zika, yellow fever, dengue and Chikungunya. Present study investigates an efficient, alternative and comparative approach for mosquito control which is safe to environment and non-target organisms. The silver nano-composites (AgNCs) were synthesized from the aqueous stem extract of Achyranthes aspera (AASE) using different concentration of aqueous silver nitrate (AgNO3). T…

Aedes albopictus (Skuse) is an important vector of chikungunya, dengue, yellow fever and Zika viruses. In the absence of anti-viral medication and with limited availability of a commercial vaccine for public heal…

Source: Parasites and Vectors – April 24, 2019Category: Microbiology Authors: Xiaojie Zhou, Chan Yang, Nian Liu, Mei Li, Ying Tong, Xiaopeng Zeng and Xinghui Qiu Tags: Research Source Type: research



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