Death From Transfusion-Transmitted Anaplasmosis Death From Transfusion-Transmitted Anaplasmosis

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In this report, a case of a fatality due to transfusion-transmitted anaplasmosis is described. Would donated blood screening have prevented this?Emerging Infectious Diseases

Source: Medscape Today HeadlinesCategory: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

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Publication date: Available online 26 August 2019Source: Ticks and Tick-borne DiseasesAuthor(s): F. Boucher, Y. Moutroifi, B. Peba, M. Ali, Y. Moindjie, A.-S. Ruget, S. Abdouroihamane, Kassim A. Madi, M. Soulé, O. Charafouddine, C. Cêtre-Sossah, E. CardinaleAbstractTick-borne diseases (TBD) occur in many temperate countries and are economically important in most tropical and subtropical areas, affecting dairy and beef cattle, as well as small ruminants. Four major tick-borne diseases have been detected in eastern and southern Africa: East Coast fever (ECF) caused by Theileria parva, Theiler 1904, anaplasmosis …

Publication date: Available online 13 July 2019Source: Small Ruminant ResearchAuthor(s): C. Jiménez, A. Benito, J.L. Arnal, A. Ortín, M. Gómez, A. López, S. Villanueva-Saz, D. LacastaAbstractOvine anaplasmosis is caused by the obligate intraerythrocytic bacteria Anaplasma ovis and the disease is characterized by anaemia, weight loss and weakness. A severe outbreak of ovine anaplasmosis was diagnosed for the first time in Spain in 2014 and, subsequently, a research was developed in order to increase de knowledge of this not-well-known disease.An experimental infection with Anaplasma ovis was carr…

Abstract
DNA from 1084 ticks collected by flagging in vegetation in Tsukuba and Moriya (Ibaraki, Japan), where several cases of canine granulocytic anaplasmosis were found, was molecularly examined for infection with the family Anaplasmataceae. Twenty-six positive samples of Anaplasmataceae-specific PCR of partial 16S rRNA gene were subjected to semi-nested PCR covering the divergent regions the gene and sequence analysis. Anaplasma phagocytophilum was detected in three pools of Haemophysalis longicornis larvae, and Anaplasma bovis from a Haemophysalis flava male. Sequences of both amplicons had highest homologies…

With the advent of newer methodologies, it has become possible to detect previously unsuspected pathogens. We wish to present a case of human granulocytic anaplasmosis that was diagnosed using 16S ribosomal RNA gene sequencing while originally investigating possible culture-negative endocarditis. This case is the first reported in humans from the province of Quebec. A brief review of means of transmission and clinical and laboratory findings as well as treatment is provided.

Conclusions/SignificanceThe use of chimeric antigenic matrices in immunoassays for anti-T.cruzi IgG antibody detection in sera of infected dogs was shown to be a promising tool for veterinary diagnosis and epidemiological studies. The chimeric antigens used in this work allowed also to overcome the common hurdles related to serodiagnosis ofT.cruzi infection, especially regarding variation of efficiency parameters according to different strains and cross-reactivity with other infectious diseases.

Type IV secretion systems (T4SS) are used by a number of bacterial pathogens to attack the host cell. The complex protein structure of the T4SS is used to directly translocate effector proteins into host cells, often causing fatal diseases in humans and animals. Identification of effector proteins is the first step in understanding how they function to cause virulence and pathogenicity. Accurate prediction of effector proteins via a machine learning approach can assist in the process of their identification. The main goal of this study is to predict a set of candidate effectors for the tick-borne pathogen Anaplasma phagocy…

In this study, two tick species, identified as Rhipicephalus microplus and Haemaphysalis longicornis based on morphological and molecular methods by analyzing COI gene, were collected from cattle, goat or sheep. Subsequently, A. bovis was initially detected by PCR amplifying the rrs gene in ticks in Shaanxi Province, China. The sequencing and Blast results showed that some false positive samples were found when only based on the amplification of partial rrs gene, presenting these sequences resembled those of other Alphaproteobacteria rather than A. bovis. Although major surface proteins genes were proposed and used success…

Source: Infection, Genetics and EvolutionCategory: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research

We report a case of a 64-year-old man presenting with a febrile illness and acute nephritis in the setting of HGA infection. The patient’s kidney biopsy was characterized by a membranoproliferative glomerulonephritis pattern and acute interstitial inflammation. After appropriate antibiotic treatment and high-dose steroids, the patient had a marked improvement in kidney function, although a subsequent recrudescence of nephritis required a 6-month course of additional steroids. As the prevalence of tick-borne diseases continues to spread across the United States, raising awareness of the potential for atypical presenta…

Abstract
Lyme borreliosis, granulocytic anaplasmosis and monocytic ehrlichiosis are well studied in humans and dogs. In horses, these diseases are not widely investigated and limited information is available about their occurrence. The purpose of this study was to present the first ELISA-based report on the seroprevalence of Anaplasma phagocytophilum, Ehrlichia spp. and Borrelia burgdorferi in horses from Northern Bulgaria. A total of 192 horses were investigated from three regions in Northern Bulgaria (Northwestern, North-Central and Northeastern Bulgaria). All equine sera were tested for A. phagocytophilum, Ehrl…

Source: Acta Veterinaria HungaricaCategory: Veterinary Research Authors: Tags: Acta Vet Hung Source Type: research

In this study, the full length of DNA encoding A. marginale MSP4 (AmMSP4) was cloned from the parasites. The open reading frame of msp4 coding sequence of Thailand strain is 849 bp. Phylogenetic analysis revealed that the msp4 coding sequence of A. marginale was highly conserved when compared with Anaplasma phagocytophilum. The recombinant plasmid was further transformed into the BL21-CodonPlus (DE3)-RIPL competent cells for over-expression of the recombinant major surface protein 4 of A. marginale (rAmMSP4). Sera from rabbit immunized with rAmMSP4 and from cattle infected with A. marginale were used to study the antigenic…

Source: Acta TropicaCategory: Infectious Diseases Authors: Tags: Acta Trop Source Type: research



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