Whole-Blood Testing for Diagnosis of Zika Virus Infections Whole-Blood Testing for Diagnosis of Zika Virus Infections

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How does whole-blood testing compare with plasma for the diagnosis of acute Zika virus infections?Emerging Infectious Diseases

Source: Medscape Today HeadlinesCategory: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

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Publication date: 3 September 2019Source: Cell Reports, Volume 28, Issue 10Author(s): Ahmed O. Hassan, Igor P. Dmitriev, Elena A. Kashentseva, Haiyan Zhao, Douglas E. Brough, Daved H. Fremont, David T. Curiel, Michael S. DiamondSummaryThe teratogenic potential of Zika virus (ZIKV) has made the development of an effective vaccine a global health priority. Here, we generate two gorilla adenovirus-based ZIKV vaccines that encode for pre-membrane (prM) and envelope (E) proteins (GAd-Zvp) or prM and the ectodomain of E protein (GAd-Eecto). Both vaccines induce humoral and cell-mediated immune responses and prevent lethality aft…

Source: Cell ReportsCategory: Cytology Source Type: research

We report transcriptome changes in genes relevant to development, vascular development, muscle, and cancer biology, which provide interesting avenues for future research.

Aedes spp. are a major public health concern due to their ability to be efficient vectors of dengue, Chikungunya, Zika and other arboviruses. With limited vaccines available and no effective therapeutic treatments against arboviruses, the control of Aedes spp. populations is currently the only strategy to prevent disease transmission. Host-associated microbes (i.e. microbiota) recently emerged as a promising field to be explored for novel environmentally-friendly vector control strategies. In particular, gut microbiota is revealing its impact on multiple aspects of Aedes spp. biology, including vector competence, thus bein…

A Danish and Taiwanese company has won Australia’s Good Design Award for a portable diagnostic device—small enough to fit in a camera case—that allows diagnosis of infectious diseases on the spot from a single drop of blood.
“The Good Design Award ranked BluBox as the best solution for the rapid and accurate assessment of communicable diseases in heavily populated as well as resource-constrained, expertise-lacking areas,” explained Filippo Bosco, CEO and one of the three founders of BluSense Diagnostics (Copenhagen).
The secret inside…

Source: MDDICategory: Medical Devices Authors: Tags: IVD Source Type: news

ABSTRACT Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause of morbidity and mortality of children in developing countries, whereas it has become rarer in developed countries due to vaccination. Its differential diagnosis should be made with other childhood viral respiratory diseases such as influenza, rhinovirus and adenovirus, and exanthematic febrile diseases such as rubella, roseola and varicella. In tropical regions, it should be performed with dengue, zika and chikungunya. Its clinical picture presents the following phases: incubation, usually asymptomatic; a prodro…

The aim of this study was to investigate what factors predict knowledge about Zika transmission, symptomology, and treatment among U.S. travelers and, additionally, to evaluate how Zika knowledge influences th…

Source: BMC Public HealthCategory: Consumer Health News Authors: Tags: Research article Source Type: research

Understanding the timing of pulse vaccinations can help in preventing Zika virus outbreaks. Researchers uncover a new seasonality effect via modeling. Winter is coming.

Source: Forbes.com Healthcare NewsCategory: Pharmaceuticals Authors: Source Type: news

CONCLUSIONS The socioeconomic status of pregnant women, especially among the less privileged, influenced the use of protective measures against Zika virus, from the purchase of repellent, clothing, insecticides to other resources in the municipality of Propri á, SE.RESUMO OBJETIVO Avaliar a ades ão de gestantes às medidas de proteção individual contra picadas de mosquitos, recomendadas pelo Ministério da Saúde e investigar os fatores associados à não adoção dessas medidas. MÉTODOS Foram entrevistadas 177 gestantes entre novembro de 2016 e f…

Source: Revista de Saude PublicaCategory: International Medicine & Public Health Source Type: research

In 2015, the Zika virus spread from Brazil throughout the Americas, posing an unprecedented challenge to the public health community. During the epidemic, international public health officials lacked reliable …

Source: BMC MedicineCategory: Internal Medicine Authors: Tags: Research article Source Type: research



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