Hi friends, looking to see if any of you have experienced the same things I have. I was on the depo shot for two and a half years. I have gained 60 pounds, have severe chronic pain and was diagnosed with fibromyalgia, and am constantly nauseous, in pain, and miserable. I have severe anxiety and depression, and the depo only made it worse. I do not bleed at all anymore. I recently stopped taking the depo and have started the cyclic progesterone method to help get things back to normal. I have had horrible withdrawal symptoms, vomiting, nausea, chills, headaches, cramps. Have any of you had the same side effects coming off of the depo shot or a similar experience?