Strain of Zika that can cause small heads in children found in Africa for the first time

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Scientists at Oxford found the link after investigating a few cases of microcephaly – a smaller than normal head size – which propped up in Angola in 2017.

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A mysterious illness that hit dozens of American and Canadian diplomats in 2016 in Havana, Cuba, is likely connected to insecticides sprayed to fight Zika virus, according to a new study from a team of scientists in Canada.

Source: CNN.com – HealthCategory: Consumer Health News Source Type: news

[Observer] — Dr. Dougbeh Chris Nyan

This study aimed to assess the impact of the Zika epidemic on the registration of birth defects in Brazil. We used an interrupted time series analysis design to identify changes in the trends in the registration of congenital anomalies. We obtained monthly data from Brazilian Live Birth Informatio n System and used two outcome definitions: 1) rate of congenital malformation of the brain and eye (likely to be affected by Zika and its complications) 2) rate of congenital malformation not related to the brain or eye unlikely to be causally affected by Zika. The period between maternal infection with Zika and diagnosis of cong…

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Chaker El Kalamouni

Zika virus (ZIKV) is an emerging mosquito-borne virus of medical concern. ZIKV infection may represent a serious disease, causing neonatal microcephaly and neurological disorders. Nowadays, there is no approved antiviral against ZIKV. Several indigenous or endemic medicinal plants from Mascarene archipelago in Indian Ocean have been found able to inhibit ZIKV infection. The purpose of our study was to determine whether essential oil (EO) from Reunion Island medicinal plant Ayapana triplinervis, whose thymohydroquinone dimethyl ether (THQ) is the main component has the potential to prevent ZIKV i…

Source: MoleculesCategory: Chemistry Authors: Tags: Article Source Type: research

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For the first 60 years following its isolation, Zika virus (ZIKV) remained a relatively poorly described member of the Flaviviridae family. However, since 2007, it has caused a series of increasingly severe outbreaks and is now associated with neurological symptoms such as Guillain-Barré syndrome and congenital Zika syndrome (CZS). A number of reports have improved our understanding of rare complications that may be associated with ZIKV infection in adults, the areas of the body to which it spreads, and viral persistence in various tissues. Likewise, studies on the effect of ZIKV infection during pregnan…

Source: VirusesCategory: Virology Authors: Tags: Review Source Type: research

[Inmunorreacción de la infección por el virus de Zika en retina de ratones].
Biomedica. 2019 Aug 01;39(Supl. 2):8-10
Authors: Rivera J, Rengifo AC, Santamaría G, Corchuelo S, Álvarez-Díaz D, Parra EA, Naizaque J, Monroy-Gómez J, Torres-Fernández O
PMID: 31529828 [PubMed – in process]

ConclusionsWe developed a ZEDIII-based ELISA that can discriminate between past or current DENV and ZIKV infections, allowing the detection of a serological scar from otherflaviviruses. This could be used to confirm exposure of pregnant women or to follow the spread of an endemic disease.

Publication date: Available online 18 September 2019Source: Social Science &MedicineAuthor(s): Yuxi Wang, Martin McKee, Aleksandra Torbica, David StucklerAbstractContemporary commentators describe the current period as “an era of fake news” in which misinformation, generated intentionally or unintentionally, spreads rapidly. Although affecting all areas of life, it poses particular problems in the health arena, where it can delay or prevent effective care, in some cases threatening the lives of individuals. While examples of the rapid spread of misinformation date back to the earliest days of scientific med…

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Flaviviruses are the most medically relevant group of arboviruses causing a wide range of diseases in humans and are associated with high mortality and morbidity, as such posing a major health concern. Viruses belonging to this family can be endemic (e.g., dengue virus), but can also cause fulminant outbreaks (e.g., West Nile virus, Japanese encephalitis virus and Zika virus). Intense research efforts in the past decades uncovered shared fundamental strategies used by flaviviruses to successfully replicate in their respective hosts. However, the distinct features contributing to the specific host and tissue tropi…

Source: VirusesCategory: Virology Authors: Tags: Review Source Type: research

Date: Tuesday, 09 24, 2019; Speaker: Dr. Rachel Abrams, NINDS; Dr. Avi Nath, NINDS; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit



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