Third-trimester ultrasound finds undetected fetal abnormalities

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Can prenatal ultrasound predict Zika infection outcomes?

AbstractPurpose of ReviewEmerging infectious diseases have seen a record increase in prevalence, and understanding their management is critical in an increasingly global community. In this paper, we review current literature detailing the role of radiology in the diagnosis and treatment of the Ebola (EVD), Zika (ZVD), Chikungunya (CHIKF), H1N1, Middle East Respiratory (MERS), and Severe Acute Respiratory Syndrome (SARS) viruses.Recent FindingsComplex protocols are required to safely use portable imaging in EVD to prevent nosocomial spread of disease. In ZVD, antenatal ultrasound can detect fetal abnormalities early, allowi…

Conclusion We found no differences in pregnancy or neonatal outcomes between women who tested positive and presumed positive for Zika virus during pregnancy. Testing of infants and placenta tissue after delivery was largely inconclusive. Improvement in testing for Zika virus infection is needed to determine which pregnancies are at risk for congenital anomalies. Further research is still needed to determine which children are at risk for poor neurodevelopmental outcomes related to Zika virus and how to best coordinate care among the immigrant population during a new disease epidemic. […] Thieme Medical Publishers 33…

Source: American Journal of PerinatologyCategory: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research

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Conclusions
Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and…

Source: Royal College of Obstetricians and Gynaecologists. Published: 2/27/2019.
This 12-page document, updated in February 2019, provides guidelines on Zika virus in pregnancy for healthcare professionals. It discusses Zika epidemiology, transmission, symptoms, and prevention. It includes advice for pregnant women and couples considering pregnancy, and recommendations for pregnant women whose partner has been to an area with risk for Zika virus transmission, and any pregnant woman with possible exposure to Zika virus, presenting with fetal ultrasound findings consistent with microcephaly.
(PDF)

Amniocentesis is useful for confirming suspected cases of fetal Zika virus infection (ZIKV) when ultrasound suggests central nervous system abnormalities and risk of ZIKV exposure is high, according to a new prospective study.Reuters Health Information

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This article is protected by copyright. All rights reserved.
PMID: 30561172 [PubMed – as supplied by publisher]



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