How the Zika virus can spread

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(Goethe University Frankfurt) The spread of infectious diseases such as Zika depends on many different factors. Researchers from Goethe University and the Senckenberg Society for Nature Research in Frankfurt were able to generate reliable maps for the transmission risk of the Zika virus in South America.

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Nature Reviews Urology, Published online: 11 November 2019; doi:10.1038/s41585-019-0260-9ZIKA virus causes prostatitis

Source: Nature Reviews UrologyCategory: Urology & Nephrology Authors: Source Type: research

We report the first case of a corneal ocular ectasia in an infant with Zika virus congenital infection (CZS). We suspect that the ocular embryology and neurotropism of the Zika virus could account for the corneal involvement.

In conclusion, the author of this paper mentioned that immunization gap needs to be handle systematically. Immunization data released on 2017 showed that complete immunization was given only to 20% of targeted group, while almost 75% were either unvaccinated or unknown. During the outbreak of diphteria in Indonesia, the WHO also reported several countries with similar problem such as Bangladesh, Haiti and Yamen. It was shown that a coordination between doctors in clinic/hospital with public health officer to conduct an epidemiological investigation, in conjunction with giving prophylaxis and assuring the logistics of anti-…

Source: Acta medica IndonesianaCategory: Internal Medicine Tags: Acta Med Indones Source Type: research

ZIKA virus cases in Europe have been confirmed after three people became infected. Which countries now carry a risk of the disease?

Conclusion: PCR evidence of infection with herpes group viruses was found in one-third of patients with hypertensive anterior uveitis; CMV being the most common pathogen. The PCR-positive group generally responded well to a combination of antiviral and anti-glaucoma treatment.
PMID: 31697590 [PubMed – as supplied by publisher]

Rampazzo R
Abstract
Arboviruses have been emerging and reemerging worldwide, predominantly in tropical and subtropical areas. As many arbovirus infections, including dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV), have similar signs and symptoms, clinical diagnosis of arbovirus infections is challenging. Therefore, reliable laboratory tests are necessary to improve the clinical management of patients with suspected arbovirus infections. Real-time reverse-transcription PCR (RT-qPCR) is among the more effective methods to distinguish these viruses. The aim of this study was to construct a unique positive exter…

Source: Biomed ResCategory: Research Authors: Tags: Biomed Res Int Source Type: research

CONCLUSION Epilepsy, irritability, dysphagia, and musculoskeletal comorbidities were the most frequent clinical variables in children with microcephaly. There was a high prevalence of congenital ZIKV microcephaly syndrome in this sample.RESUMO OBJETIVO Pretende-se, neste estudo, identificar a preval ência de variáveis clínicas em crianças com microcefalia. MÉTODOS Trata-se de um estudo transversal e observacional com dados coletados de prontuários de pacientes admitidos no ambulatório de microcefalia de um centro de referência em Teresina (PI). Foram coletados dados dem…

Rice
Stefan G. Sarafianos

RNA viruses are highly successful pathogens and are the causative agents for many important diseases. To fully understand the replication of these viruses it is necessary to address the roles of both positive-strand RNA ((+)RNA) and negative-strand RNA ((−)RNA), and their interplay with viral and host proteins. Here we used branched DNA (bDNA) fluorescence in situ hybridization (FISH) to stain both the abundant (+)RNA and the far less abundant (−)RNA in both hepatitis C virus (HCV)- and Zika virus-infected cells, and combined these analyses with visualization of viral pro…

Source: VirusesCategory: Virology Authors: Tags: Article Source Type: research

Publication date: Available online 7 November 2019Source: Chemical Engineering JournalAuthor(s): Benita Ortega-Berlanga, Luis Hernández-Adame, César del Angel-Olarte, Fernanda Aguilar, Sergio Rosales-Mendoza, Gabriela PalestinoAbstractNew adjuvants are required in the field of vaccinology to enhance the immunogenicity and efficacy of subunit vaccines, which constitute a safer approach to protect against infectious diseases compared to whole pathogen-based vaccines. In the present study, rare-earth upconverting microparticles were explored as possible antigen carriers with adjuvant properties by using a peptid…

The finding of a new study in mice could lead to an effective treatment for the West Nile and Zika viruses, even once they have reached the nervous system.

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