Two people got the plague in China. Why is it still a thing?


Two people in China are being treated for plague, authorities said Tuesday. It’s the second time the disease, the same one that caused the Black Death, one of the deadliest pandemics in human history, has been detected in the region — in May, a Mongolian couple died from bubonic plague after eating the raw kidney of a marmot, a local folk health remedy.

Source: – HealthCategory: Consumer Health News Source Type: news

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ConclusionThese results suggested that IFN-γ plays an important role in acute lung injury induced by severe influenza A(H1N1)pdm09 infection, and monoclonal antibodies against IFN-γ could be useful as a potential therapeutic remedy for future influenza pandemics.

Current challenges: from the path of “original antigenic sin” towards the development of universal flu vaccines.
Int Rev Immunol. 2019 Nov 09;:1-16
Authors: Biswas A, Chakrabarti AK, Dutta S
Annual flu led by influenza viruses is contemplated to be one of the foremost global health challenges due to its rapid spread leading to the life-threatening epidemic or pandemic. An enormous number of people die due to flu and its associated intricacies every year. Annual vaccination is considered to be the gold standard strategy to protect the individual from acquiring infection and further de…

Authors: Li S, Di D, Wu X, Zhang L, Liu R, Huang Q, Pan H, Ye D, Leng R
Recent large-scale genetic association studies have identified that several single nucleotide polymorphisms (SNPs) on X chromosome are correlated with risk of systemic lupus erythematosus (SLE) in Chinese population. The aim of this study was to estimate association between these loci and clinical features in female patients with SLE. Six SNPs identified in previous studies were genotyped. Odds ratio (OR) was calculated with adjusting for potential confounding factors. A total of 772 SLE patients were included in the final analysis. Th…

Source: AutoimmunityCategory: Allergy & Immunology Tags: Autoimmunity Source Type: research

Deer-hide gelatin (DHG) is an important animal-derived traditional Chinese medicine (TCM), which has been applied in TCM for over 400 years. However, it is extremely difficult to distinguish DHG with adulteration or made with other animal skins due to the highly processing procedure. Therefore, a simple strategy for identifying species-specific peptide biomarkers in deer-hide gelatin (DHG) is needed. In the present study, untargeted and targeted mass spectrometry approaches were implemented to analyze comprehensive peptidomic profiles of trypsin-digested animal gelatins. Mathematics set theory was then us…

Source: Analytica Chimica ActaCategory: Chemistry Authors: Tags: Anal Chim Acta Source Type: research

(Natural News) From malaria, to Ebola, or even the flu, tons of diseases break out and kill hundreds or even thousands of people every year. Any of these diseases could easily turn into an epidemic. For example, in 2017 an outbreak of the bubonic plague – the same plague that killed 60 percent of Europe…

Source: NaturalNews.comCategory: Consumer Health News Source Type: news

CONCLUSIONS: The first of the three hypotheses about its origins is the Columbian hypothesis, which states that Columbus’s crew acquired syphilis from Native Americans and carried it back to Europe in 1493 A. D. On the contrary, the second hypothesis (pre-Columbian) asserts that syphilis was present in Europe long before Columbus’s voyage and was transferred to the New World by Columbus’s men. The Unitarian theory argues that syphilis, bejel, yaws, and pinta are not separate diseases but they represent syndromes caused by slightly different strains of one organism. Nowadays, Syphilis’ origin is still uncertain and remains …

This article evaluates the textual evidence for bubonic plague in classical antiquity from medical sources and discusses methodologies for “retrospective diagnosis” in light of new developments in microbiology. A close study of Greek medical texts suggests that bubonic plague was unfamiliar to medical writers until sometime before the second century AD, when sources cited by Rufus of Ephesus report a disease that resembles bubonic plague. Rufus of Ephesus describes this disease around AD 100, and Aretaeus (fl. ca. AD 50 or 150) appears to describe the same disease as well. Intriguingly, the disease then disappear…

Source: Medical HistoryCategory: History of Medicine Authors: Tags: Bull Hist Med Source Type: research

Qingwen Zhang1†, Youquan Xin1†, Haihong Zhao1, Rongjiao Liu2, Xiaoqing Xu1, Yanfeng Yan2, Zhipeng Kong1, Tong Wang2, Zhizhen Qi1, Qi Zhang1, Yang You2, Yajun Song2, Yujun Cui2, Ruifu Yang2*, Xuefei Zhang1* and Zongmin Du2*

1Qinghai Institute for Endemic Disease Prevention and Control, Xining, China
2State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

Yersinia pestis is the etiological agent of the notorious plague that has claimed millions of deaths in history. Of the four known Y. pestis biovars (Antiqua, Medievalis, Orientalis, and …

Have you ever thought that it would be possible to monitor drug overdoses, Zika cases or the spread of the flu in real time? Have you ever imagined that satellites wouldbe able to tell how and where a malaria epidemic will happen months before the actual outbreak? It is mind-blowing how, in the last years, digital maps developed to a level where they serve as effective tools for evaluating, monitoring and even predicting health events. That’s why I decided to give a comprehensive overview of digital maps in healthcare.

John Snow, cholera and the revolution of maps in healthcare
Before Game of Thrones monopolized Joh…

Source: The Medical FuturistCategory: Information Technology Authors: Tags: Future of Medicine Healthcare Design Mobile Health digital health digital technology epidemics epidemiology gc4 Innovation interactive maps Source Type: blogs

Authors: Rigau-Pérez JG
The history of the US Public Health Service (PHS) is usually presented in terms of diseases or discoveries; this article examines twenty years’ activity in one location. When the United States invaded Puerto Rico in 1898, the Marine Hospital Service (now PHS) took responsibility for foreign quarantine, inspection of immigrants, and medical care for merchant seamen. Its officers evaluated the sanitary conditions of port cities, helped reorganize local disease surveillance and control, and investigated endemic diseases (e.g., hookworm-related anemia) and epidemics (e.g., buboni…

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