Anal cancer rates and mortality have risen dramatically among Americans

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(University of Texas Health Science Center at Houston) Rates of new anal cancer diagnoses and deaths related to human papillomavirus (HPV), the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of their study were published in the November issue of the Journal of the National Cancer Institute.

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AbstractIn the U.S. there is an epidemic of sexually transmitted diseases (STIs). One of the most prevalent STIs is the Human Papillomavirus (HPV). Certain high risk strains of HPV are believed to cause virtually all cervical cancers, over 90% of anal cancers, 70% of oropharyngeal cancers, and the majority of anal  genital warts. HPV is preventable through vaccination and is available for both men and women. Several educational interventions have been employed, yet baseline awareness and knowledge related to HPV and 9vHPV remains relatively low among young men. What is not known is the most effective method for provid…

Recently, Desperate Housewives star Marcia Cross made headlines by discussing her diagnosis of anal cancer and her husband ’s diagnosis of throat cancer, revealing that both had been related to the human papillomavirus, or HPV. The move was brave, as the actress broke free from the stigma related to anal cancer and sexually transmitted diseases. More […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.

Source: Kevin, M.D. – Medical WeblogCategory: General Medicine Authors: Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs

Introduction: Anal cancer screening has not been adopted by Taiwanese care providers. The study aim was to explore the differences of anal cytology and HPV detection among men with and without HIV.Methodology: In this case-control study, men with HIV who attended one of the outpatient clinics of Taoyuan General Hospital were enrolled as cases. Men who had experienced condomless sex and tested HIV negative were enrolled as controls. Anal swabs were collected for thin-preparation anal cytology and HPV genotyping.Results: A total of 288 men who had tested positive for HIV and 208 who had tested HIV negative were enrolled; 75%…

Human papillomavirus (HPV) causes cervical cancer, anal cancer, vulvar cancer, vaginal cancer, penile cancer and oropharyngeal cancer. SCC in the genital region in particular is recognized to be caused by HPV infection, and intraepithelial lesions of the penis and vulva are termed penile intraepithelial neoplasia (PIN) and vulvar intraepithelial neoplasia (VIN), respectively. Although SCC of the nail apparatus is recognized as being associated with high-risk HPVs, it is not well-known in general medicine, and its analysis has been insufficient.

Human papillomavirus (HPV) causes cervical cancer, anal cancer, vulvar cancer, vaginal cancer, penile cancer, and oropharyngeal cancer. Squamous cell carcinoma (SCC) in the genital region in particular is recognized to be caused by HPV infection, and intraepithelial lesions of the penis and vulva are termed penile intraepithelial neoplasia and vulvar intraepithelial neoplasia, respectively. Although SCC of the nail apparatus is recognized as being associated with high-risk HPVs, it is not well-known in general medicine, and its analysis has been insufficient.

Conclusion
Though there is high prevalence of anal HPV in men who have sex with men living with human immunodeficiency virus, there was also a high incidence of HRHPV vaccine types in the 2-year follow-up, indicating potential for prevention if these men were not previously infected with HPV vaccine types and were vaccinated at their baseline visit.

This article aims to review the microbiology, pathophysiology, epidemiology, clinical presentation, diagnostic evaluation, prophylaxis and treatment options for HPV as an etiology agent in anal cancers in light of recent literature.

Source: Journal of Infection and Public HealthCategory: International Medicine & Public Health Authors: Source Type: research

ConclusionsThe present work estimated the cost of HPV-related diseases for hospitalized patients in two Italian regions. The considerable estimated annual economic burden is a powerful driver for the governance of the public health sector.

Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and is a well-known cause of oropharyngeal, cervical, vaginal, vulvar, penile, and anal cancers. Despite the proven efficacy of the HPV vaccine, vaccination rates remain persistently low. Much literature has focused on attitudes toward the HPV vaccine; however, researchers have also investigated strategies clinicians can use to improve vaccination attitudes and acceptance. Such strategies include provider education, vaccine reminder/recall, and chart audit and feedback.

Source: Journal of Pediatric Health CareCategory: Pediatrics Authors: Tags: Department Source Type: research

Women, especially black women, might face a greater chance of dying of cervical cancer than previously thought, according to a study published Monday in the journal Cancer.
Estimates from previous studies may have been artificially low because they included women who had had hysterectomies, a procedure to remove the uterus. The new study suggests that black women are dying at a rate 77 percent higher, and white women are dying at a rate 47 percent higher, than researchers had previously thought. After adjusting for hysterectomies, cervical cancer killed 10 out of every 100,000 black women and approximately 5 out …

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