Anal Cancer Rates, Deaths Are Climbing, Study Finds

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Source: AARP.org NewsCategory: American Health Source Type: news

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[New Zimbabwe] Divorced by her husband of 15 years after being diagnosed with anal cancer, further rejected by relatives and friends, a Chiredzi woman felt it was time to leave the hospital so she could “go back home and die”.

SummaryHuman papilloma virus (HPV) is a  DNA virus consisting of approximately 8000 base pairs. HPV represents the most common sexually transmitted infection worldwide. Around 200 different genotypes exist. They are distinguished into low- and high-risk genotypes, depending on the risk of such HPV-associated lesions undergoing malignant transformation. The high-risk genotypes include HPV 16 and 18, which are responsible for a variety of human cancers. The most common malignancies that are associated with HPV infection are cervical cancer, oropharyngeal cancer and anal cancer. Screening for HPV precursor…

AbstractPurpose of ReviewAlthough uncommon, locally recurrent rectal cancer (LRRC) and locally recurrent anal cancer (LRAC) after definitive chemoradiation can confer high morbidity and mortality. Although surgery is critical for management, recent studies show promising results with other locally directed and/or systemic treatment approaches. Here we review the literature to examine recent advances in management of this patient population.Recent FindingsFor LRRC, studies demonstrate success with newer surgical approaches and redefine contraindications for surgery. The roles of brachytherapy, repeat external beam irradiati…

ConclusionNGS ‐based approach is more accurate than PCR‐based HPV testing for identifying HIV+ MSM at risk for developing AC. We raise the concern regarding the efficacy of current HPV vaccines for preventing AC in this high‐risk population.

Source: Cancer MedicineCategory: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research

Researchers warn that the incidence and mortality rates of anal cancer have been increasing steeply in the United States over a period of only 15 years.

Title: HPV Blamed for Rising Rates of Anal CancerCategory: Health NewsCreated: 11/20/2019 12:00:00 AMLast Editorial Review: 11/21/2019 12:00:00 AM

WEDNESDAY, Nov. 20, 2019 — There has been an increase in the incidence of squamous cell carcinoma of the anus (SCCA) in the United States, according to a study published online Nov. 19 in the Journal of the National Cancer Institute.
Ashish A….

Anal cancer cases and deaths are rising dramatically in the United States, especially among older people and young black men, a new study says.

Source: CNN.com – HealthCategory: Consumer Health News Source Type: news

A little over half of US teens are up-to-date on HPV vaccinations that prevent 90% of anal cancer cases, but rates are rising among older Americans University of Texas researchers found.

(University of Texas Health Science Center at Houston) Rates of new anal cancer diagnoses and deaths related to human papillomavirus (HPV), the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of their study were published in the November issue of the Journal of the National Cancer Institute.

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