PET/CT plays role in lung adenocarcinoma management

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(American Roentgen Ray Society) According to an article published in the American Journal of Roentgenology (AJR), FDG PET, combined with high-resolution CT, has value for predicting invasive histopathologic subtypes, but there was no significance for predicting invasive growth patterns of early lung adenocarcinoma.

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Conditions:   Endometrial Endometrioid Adenocarcinoma;   Stage I Uterine Corpus Cancer AJCC v8;   Stage IA Uterine Corpus Cancer AJCC v8;   Stage IB Uterine Corpus Cancer AJCC v8;   Stage II Uterine Corpus Cancer AJCC v8 Interventions:   Radiation: External Beam Radiation Therapy;   Radiation: Internal Radiation Therapy;   Biological: Pembrolizumab;   Other: Quality-of-Life Assessment;   Other:&nb…

Source: ClinicalTrials.govCategory: Research Source Type: clinical trials

AbstractThe clinical application of photodynamic therapy (PDT) for gastrointestinal (GI) neoplastic lesions has been developed with appreciation for the great efforts and kind support of Dr. Tom Dougherty and his followers ’ contributions. There are several published studies on clinical PDT in the field of GI oncology. Esophageal cancer was one of the first clinical indications for PDT that was approved as an endoscopic procedure in both the United States and Japan. PDT was initially used as a palliative local treat ment for patients with obstructive esophageal cancer. PDT is also indicated for eradicative therapy fo…

Source: Photochemistry and PhotobiologyCategory: Science Authors: Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research

Conclusions: Our findings strongly emphasize the importance of random, four-quadrant biopsy in the detection of not only low-grade dysplasia, but also high-grade dysplasia and early invasive carcinoma as part of Barrett’s oesophagus surveillance.
PMID: 31880176 [PubMed – as supplied by publisher]

Authors: Hurtado Pardo L, Cienfuegos JA, Antoñanzas J, Valentí V, Benito A, Pardo F, Martínez Regueira F, Zozaya G, Martí-Cruchaga P, Lozano MD, Subtil JC, Rotellar F
Abstract
OBJECTIVE: the objective of the present study was to analyze the characteristics of resected incidental lesions of the pancreas.
MATERIAL AND METHODS: a retrospective study was performed of pancreatectomies due to incidentalomas between 1995 and 2018.
RESULTS: one hundred pancreatectomies were performed due to incidental lesions; 64 (64%) were solid and 36 (36%) were cystic lesions. The cytological analysis…

Conclusions: These results suggest that a subset of polymorphisms known to be associated with the risk of lung cancer in female never smokers is also associated with the risk of lung cancer in male smokers.
PMID: 31878769 [PubMed – as supplied by publisher]

Source: The Korean Journal of Internal MedicineCategory: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research

AbstractPurposeWe combined conventional clinical and pathological characteristics and pathological architectural grading scores to develop a prognostic model to identify a specific group of patients with stage I lung adenocarcinomas with poor survival following surgery.MethodsThis retrospective study included 198 patients with stage I lung adenocarcinomas recruited from 2004 to 2013. Multivariate analyses were used to confirm independent risk factors, which were checked for internal validity using the bootstrapping method. The prognostic scores, derived from β-coefficients using the Cox regression model, classified pa…

Publication date: Available online 26 December 2019Source: Food Research InternationalAuthor(s): Armin Tarrah, Vinícius da Silva Duarte, Shadi Pakroo, Viviana Corich, Alessio GiacominiAbstractIn this work, we studied the genomes and characterized some probiotic features of four S. macedonicus strains isolated from dairy environments in Italy that already had indicated some technological potential. The genomes of these strains were sequenced and used for genomic in silico studies. All strains were also evaluated for hemolytic activity, susceptibility to most commonly used antibiotics and probiotic potential, such as …

Conclusion:
Despite the rare occurrence of metastases in the oral region, the dental surgeon should be aware of the possibility for correct diagnostic conduction and, subsequently, the institution of treatment in the early stages of disease.

Publication date: Available online 26 December 2019Source: Journal of Geriatric OncologyAuthor(s): Richard Li, Jessica Vazquez, Jennifer Novak, Mina Sedrak, Susanne Warner, Scott Glaser, Yi-Jen Chen, William Dale, Arya AminiAbstractIntroductionOlder adults are underrepresented in landmark trials that determine treatment guidelines for pancreatic cancer. We used the National Cancer Database (NCDB) to compare treatment patterns and outcomes in stage I-III pancreatic cancer between older adult patients, defined as age 80 or older, to patients younger than 80.Material and MethodsWe identified 140,678 patients in the NCDB diagn…



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