Reclassification of aspergillosis phenotype in adult CF patients & 10 year follow up data


AbstractBackgroundAllergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease caused by a hypersensitivity reaction to Aspergillus colony in the airways. Due to the diversity of disease manifestations and physicians ’ incomplete knowledge of ABPA, patients with ABPA are often misdiagnosed and given poor prognosis.ObjectivesTo investigate the clinical characteristics, treatment and prognosis status among patients with ABPA.MethodsWe retrospectively analyzed 75 patients diagnosed as ABPA in Zhongshan Hospital, Fudan University between October 2008 and June 2018.ResultsAmong 75 patients, 28% had asth…

Source: The Clinical Respiratory JournalCategory: Respiratory Medicine Authors: Tags: ORIGINAL ARTICLE Source Type: research

by Patr ícia Alves de Castro, Ana Cristina Colabardini, Adriana Oliveira Manfiolli, Jéssica Chiaratto, Lilian Pereira Silva, Eliciane Cevolani Mattos, Giuseppe Palmisano, Fausto Almeida, Gabriela Felix Persinoti, Laure Nicolas Annick Ries, Laura Mellado, Marina Campos Rocha, Michael Bromley, Roberto Nasci mento Silva, Gabriel Scalini de Souza, Flávio Vieira Loures, Iran Malavazi, Neil Andrew Brown, Gustavo H. GoldmanAspergillus fumigatus causes invasive aspergillosis, the most common life-threatening fungal disease of immuno-compromised humans. The treatment of disseminated infections with antifungal d…

Source: PLoS GeneticsCategory: Genetics & Stem Cells Authors: Source Type: research

Source link