Zimbabwe: Anthrax Outbreak Hits Masvingo


[The Herald] An outbreak of anthrax has hit Bikita District in Masvingo with 28 people reportedly diagnosed with the disease at different clinics so far.

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[The Herald] Three are people battling for their lives after consuming meat from animals that died of anthrax in Mahusekwa, Marondera district.

Publication date: Available online 9 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Yuanyuan Liu, Yongqin Li, Qiaoxia Wang, Jianjun Fu, Fanpu JiAbstractChina’s compulsory annual livestock anthrax vaccination policy has remarkably reduced but not completely eradicated human anthrax infections. Herein we describe a sporadic human cutaneous anthrax outbreak involving two cases in 2018 in Shaanxi Province, both involving herdsman who dealt with unvaccinated and potentially sick cattle. Both patients showed Bacillus anthracis-positive blister smear and blood culture. Treatment with penicillin w…

This study highlights the phylogenetic structure of NCP B. anthracis strains with distinctive SNP branches important for forensic tracing and novel SNP discovery purposes. The sequenced strains will serve as a means to further trace the dissemination of B. anthracis outbreaks in NCP, South Africa, and on the continent, as well as for forensic tracking on a global scale.
PMID: 31866402 [PubMed – as supplied by publisher]

Source: Infection, Genetics and EvolutionCategory: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research

Abstract
Bacillus anthracis, the causative pathogen of anthrax, is a spore-forming, environmentally maintained bacterium that continues to be a veterinary health problem with outbreaks occurring primarily in wildlife and livestock. Globally, the genetic populations of B. anthracis include multiple lineages, and each may have different ecological requirements and geographical distributions. It is, therefore, essential to identify environmental associations within lineages to predict geographical distributions and risk areas with improved accuracy. Here, we model the ecological niche and predict the geography of the…

Source: Am J Trop Med HygCategory: Infectious Diseases Authors: Tags: Am J Trop Med Hyg Source Type: research

More than 100 elephants have died in Botswana in the past two months partly because of a suspected anthrax outbreak, the government said on Tuesday.

Source: Reuters: HealthCategory: Consumer Health News Tags: healthNews Source Type: news

Conclusions: Rainfall induced cycling of pH and calcium in soils plays a plausible role in amplifying spore load and persistence in endemic anthrax zones. Observed evidence of B. anthracis favoring soil alkalinity and high soil calcium levels in the environment were linked to physiological conditions that promote bacterial growth, survival, toxin secretion and spore formation; illustrating the utility of bringing laboratory-based (controlled) microbiology experiments into the fold of zoonotic disease ecology.

Conclusion: The conventional and real-time PCR methods are suitable for both the clinical and the epidemiological practice.

Source: Indian Journal of Medical MicrobiologyCategory: Microbiology Authors: Source Type: research

Abstract
Early detection of toxic proteases in food matrices plays a major role in preventing the occurrence of diseases as well as outbreaks. However, on-site detection of proteases, for instance, botulinum, anthrax and cholera in food matrices remains challenging due to their extremely low lethal dose levels. Here, we report a lateral flow assay (LFA) in a dipstick format for on-site visual detection of proteases in food matrices. The light chain of BoNT serotype A (BoNT/A LC) is used as a model system for validation of the proposed assay using magnetic beads conjugated to a synthetic peptide that provide a spec…

Source: Analytica Chimica ActaCategory: Chemistry Authors: Tags: Anal Chim Acta Source Type: research

We describe a recent anthrax outbreak involving two cows from the same herd. …

Source: BMC Veterinary ResearchCategory: Veterinary Research Authors: Tags: Case Report Source Type: research

[Govt of SA] The Veterinary Authority of Lesotho has reported three anthrax outbreaks to the World Organisation for Animal Health (OIE). The first outbreak started on 12 May 2019 and a total of 24 cattle were reported to have died of anthrax.



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